Next Generation Sequence Analysis on Cloud @ ECCB 2010

Next generation sequencing presents new challenges in large scale data processing. By combining Taverna scientific workflows with computing power from the Amazon cloud, the myGrid team in collaboration with Dr Noyes of the Animal Sciences & Physiology Research Group at the University of Liverpool, have created a powerful next generation sequencing application for whole genome Single Nucleotide Polymorphism (SNP) analysis. Through a Web Portal, the application allows scientists to upload their input data, fire off a number of parallel cloud instances for the analysis, monitor progress and collect results.

Preliminary work on the genetic variation of African cattle showed we can run a whole genome of ~22 million SNPs in a matter of hours. The application was demonstrated at the European Conference of Computational Biology (ECCB) 2010 in Ghent, Belgium – see the video from the demonstration.